These patients are also at increased risk of bowel cancer. A colonoscopy is a procedure in which doctors can look into the entire colon and collect tissue through the scope. Cancer is a group of abnormal cells, known as a tumor, that grow uncontrollably. Often, colon cancer does not give any signs at all until the late stages of the disease.
As the tumor spreads, it can cause other types of problems in the body Hereditary colon cancer essay as liver pains, loss of appetite, or other cancer of the organs. The stomach and small intestine are less commonly affected. People with HNPCC often have at least three family members and two generations with colorectal cancer, and cancer develops before age Inresearchers made a significant breakthrough in the diagnosis of FAP.
Ashkenazi Jews and Colorectal Cancer Jewish people who are Ashkenazi, or of Eastern European descent, are at increased risk for colorectal cancer. Colorectal cancer is called "hereditary" or "inherited" when several generations of a family have colorectal cancer.
Colon cancer can be diagnosed in many different ways. Patients may have anywhere from five to polyps, or growths, mostly in the colon and rectum, which usually begins before the age of The growths can become malignant or can cause obstruction of the bowel.
One way it can be tested is by having a colonoscopy. Families considered to be "HNPCC families" must display certain criteria indicating a pattern of colon cancer throughout generations.
If you suspect that you are at risk for an inherited form of colorectal cancer, talk to your doctor. Number of genes mutated. One copy of each gene comes from your mother; the other comes from your father. They identified the gene -- called APC -- that is responsible for the condition.
For those who develop a new gene mutation, it is possible to pass the FAP gene onto their children. Health care providers can evaluate the pattern of colorectal cancer in relatives in order to determine if the family has HNPCC.
Screening for blood in stool is recommended for people over the age of fifty even if they have no risk factors. Ashkenazi Jews make up the majority of the Jewish population in the U.
At least 3 members with a Lynch syndrome-related cancer At least 2 successive generations with this type of cancer Two family members with the disease are first-degree relatives i.
A gene is a block of DNA that holds the genetic code, or instructions, for producing proteins vital to our bodily functions. In HNPCC, affected people have fewer polyps, but these polyps can become cancerous more quickly than normal.
Unfortunately, not many are getting tested for the disease until it is too late. Families in which this gene mutation occurs may or may not have one or more family members with colorectal cancer or polyps.
Genes are tiny segments of DNA that control how cells function, such as telling them when to divide and grow. Colon cancer is the second most common cancer death in the United States.
Colon cancer, also known as colorectal cancer, arises in the lining of the large intestine and rectum. Ashkenazi Jews and Colorectal Cancer One of the risk factors for colorectal cancer is a family history of the disease. Screening for other Lynch syndrome-related cancers should also be performed.
In HNPCC, there are several gene, mutations which may be responsible for the development of the condition. It is important to know these layers because the staging of colorectal cancer relates to the degree of penetration of the tumor through the bowel wall.
That is where a small tube is used to take a sample of tissue without making an incision, and the tissue is examined for cancer under a microscope. FAP is characterized by the presence of more than benign polyps. Continued Other Forms of Inherited Polyposis Syndromes There are other, very rare forms of inherited polyposis syndromes that are associated with an increased risk of colorectal cancer.Hereditary Nonpolyposis Colorectal Cancer (HNPCC), also known as Lynch syndrome.
Nonpolyposis colorectal cancer, HNPCC, is the most common form of hereditary colon cancer, accounting for about 3% of all colorectal cancer diagnoses each year.
People with HNPCC often have at least three family members and two generations with colorectal. Colon cancer of the large bowel, or colon and rectum is highly treatable and often a curable disease when it is localized and diagnosed in its early stages.
Ten percent of all cancer in the United States involve either the colon or the rectum.(Fisher) Colorectal cancer is the fourth commonly /5(5). Colon Cancer Essay. Colon Cancer Cancer is considered a genetic disease. Cancer is a group of abnormal cells, known as a tumor, that grow uncontrollably.' Cancerous tumors invade and destroy surrounding tissue.
Cancer is named according to the type of organ tissue from which it develops. The genes that cause hereditary cancer are often the same ones that are mutated in sporadic cancers. For example, people with the hereditary cancer syndrome called Li-Fraumeni have a mutation in a gene called p Mutations in p53 are also commonly found in sporadic cancers.
Hereditary Colorectal Cancer Syndromes and Genetic Testing Essay - The adenomatous polyposis syndromes The genetically defined adenomatous polyposis syndromes comprise familial adenomatous polyposis (FAP), MYH-associated polyposis (MAP) and the recently described condition polymerase proofreading-associated polyposis (PPAP).
Colon Cancer Essay Examples.
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